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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cancersp</journal-id><journal-title-group><journal-title xml:lang="ru">Южно-Российский онкологический журнал/ South Russian Journal of Cancer</journal-title><trans-title-group xml:lang="en"><trans-title>South Russian Journal of Cancer</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2686-9039</issn><publisher><publisher-name>АНО "Перспективы онкологии"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.37748/2687-0533-2020-1-1-6</article-id><article-id custom-type="elpub" pub-id-type="custom">cancersp-42</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Клинические наблюдения</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASE REPORTS</subject></subj-group></article-categories><title-group><article-title>ЛЕЧЕНИЕ ЛОКАЛИЗОВАННОГО РАКА ПОЧКИ</article-title><trans-title-group xml:lang="en"><trans-title>TREATMENT OF LOCALIZED RENAL CANCER</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4468-3670</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кульченко</surname><given-names>Н. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Kulchenko</surname><given-names>N. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кульченко Нина Геннадьевна — кандидат медицинских наук, врач-уролог, врач ультразвуковой диагностики, старший преподаватель кафедры гистологии, цитологии и эмбриологии Медицинского института</p><p>117198, , г. Москва, ул. Миклухо-Маклая, д. 6  </p><p>SPIN: 1899-7871  </p></bio><bio xml:lang="en"><p>Nina G. Kulchenko — Cand. Sci. (Med.), Urologist, Senior Lecturer, Department of Histology, Cytology and Embryology</p><p>6 Miklukho-Maklaja str., Moscow 117198</p><p>SPIN: 1899-7871   </p></bio><email xlink:type="simple">kle-kni@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Российский университет дружбы народов»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Peoples Friendship University of Russia (RUDN University)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>07</day><month>03</month><year>2020</year></pub-date><volume>1</volume><issue>1</issue><fpage>69</fpage><lpage>75</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кульченко Н.Г., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Кульченко Н.Г.</copyright-holder><copyright-holder xml:lang="en">Kulchenko N.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.cancersp.com/jour/article/view/42">https://www.cancersp.com/jour/article/view/42</self-uri><abstract><p>Почечно-клеточный рак (ПКР) часто встречается в 3,9% среди онкологических заболеваний. В России, в 2018 г. было зарегистрировано 24 291 новых случаев заболевания ПКР, а в США – 63 990. Наиболее распространенным подходом к лечению ПКР ранней стадии – это радикальная нефрэктомия, или резекция почки. В этой статье представлен клинический случай успешного хирургического лечения локализованного ПКР Т3 аN0M0 у мужчины 65 лет. Через 8 недель после резекции почки биохимические показатели крови и скорость клубочковойфильтрации достоверно не отличались от исходных значений (р &gt; 0,05). При контрольной КТ брюшной полости и забрюшинного пространства (через 12 недель) увеличенных регионарных, парааортальных и параковальных лимфатических узлов не выявлено. Резекция почки является альтернативным хирургическим лечением локализованных форм ПКР, так как обеспечивает максимальную сохранность органа. Резекцию почки следует предпочитать нефрэктомии (когда это технически и стратегически возможно), поскольку данный вид вмешательства обеспечивает лучшее сохранение функции почек, не увеличивая риск послеоперационных осложнений.</p></abstract><trans-abstract xml:lang="en"><p>Renal cell carcinoma (RCC) accounts for 3.9 % of all cancers. In 2018, 24,291 and 63,990 new cases of RCC were recorded in Russia and the US, respectively. The most common approach to early stage RCC treatment consists in either radical or partial nephrectomy. This article presents a clinical case of the successful treatment of a localized renal cell carcinoma T3аN0M0 in a 65-year-old man. 8 weeks after the performed kidney resection, the biochemical blood parameters and glomerular filtration rate did not significantly differ from the initial values (p &gt; 0.05). A control CT examination of the abdominal cavity and the retroperitoneal space (after 12 weeks) detected no enlarged regional, paraaortic and paracanal lymph nodes. Partial nephrectomy is considered to be an alternative surgical treatment of localized RCC forms due to its potential for maximal organ preservation. Partial nephrectomy should be a method of choice in cases where it is technically and strategically feasible, since this type of surgical intervention provides for a better preservation of renal function under a lower risk of postoperative complications.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>почечно-клеточный рак</kwd><kwd>резекция почки</kwd><kwd>функция почки</kwd><kwd>компьютерная томография почки</kwd><kwd>малоинвазивное хирургическое лечение</kwd><kwd>скорость клубочковой фильтрации</kwd></kwd-group><kwd-group xml:lang="en"><kwd>renal cell carcinoma</kwd><kwd>partial nephrectomy</kwd><kwd>kidney function</kwd><kwd>computed tomography</kwd><kwd>minimally invasive surgery</kwd><kwd>glomerular filtration rate</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Сафронова Е. Ю., Нюшко К. М., Алексеев Б. Я., Калпинский А. С., Поляков В. А., Каприн А. Д. 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