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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cancersp</journal-id><journal-title-group><journal-title xml:lang="ru">Южно-Российский онкологический журнал/ South Russian Journal of Cancer</journal-title><trans-title-group xml:lang="en"><trans-title>South Russian Journal of Cancer</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2686-9039</issn><publisher><publisher-name>АНО "Перспективы онкологии"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.37748/2687-0533-2020-1-2-4</article-id><article-id custom-type="elpub" pub-id-type="custom">cancersp-55</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>О РАСШИРЕНИИ ВАРИАНТОВ ИСПОЛЬЗОВАНИЯ МЫШЕЙ BALB/C NUDE ДЛЯ ЭКСПЕРИМЕНТАЛЬНОГО ИЗУЧЕНИЯ ЗЛОКАЧЕСТВЕННЫХ ОПУХОЛЕЙ ЧЕЛОВЕКА IN VIVO</article-title><trans-title-group xml:lang="en"><trans-title>ABOUT EXPANDING OPTIONS FOR USING BALB/C NUDE MICE FOR EXPERIMENTAL STUDY OF HUMAN MALIGNANT TUMORS IN VIVO</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8832-8219</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жукова</surname><given-names>Г. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhukova</surname><given-names>G. V.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>Dr. Sci. (Biol.), Senior Researcher at the Testing Laboratory Center </p><p>SPIN: 1887–7415, AuthorID: 564827, </p><p>Scopus Author ID: 7005456284, Researcher ID: Y-4243–2016</p><p>63 14 line str., Rostov-on-Don 344037, Russian Federation </p></bio><email xlink:type="simple">galya_57@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2943-7655</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шихлярова</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Shikhliarova</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.б.н., профессор, старший научный сотрудник испытательного лабораторного центра </p><p>SPIN: 6271–0717, Author ID: 6507723229 344037, Российская Федерация, г. Ростов-на-Дону, ул. 14-я линия, д. 63 </p></bio><bio xml:lang="en"><p>Dr. Sci. (Biol.), Professor, Senior Researcher at the Testing Laboratory Center </p><p>SPIN: 6271–0717, AuthorID: 482103, Scopus Author ID: 6507723229</p><p>63 14 line str., Rostov-on-Don 344037, Russian Federation </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0874-5261</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сагакянц</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Sagakyants</surname><given-names>A. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.б.н., доцент, руководитель лаборатории иммунофенотипирования опухолей </p><p>SPIN: 7272–1408, Author ID: 24329773900, Researcher ID: M-8378–2019 344037, Российская Федерация, г. Ростов-на-Дону, ул. 14-я линия, д. 63 </p></bio><bio xml:lang="en"><p>Cand. Sci. (Biol.), Associate Professor, Head of the Tumor Immunophenotyping Laboratory </p><p>SPIN: 7272–1408, AuthorID: 426904, </p><p>Scopus Author ID: 24329773900, Researcher ID: M-8378–2019</p><p>63 14 line str., Rostov-on-Don 344037, Russian Federation </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6364-1794</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Протасова</surname><given-names>Т. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Protasova</surname><given-names>T. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.б.н., научный сотрудник испытательного лабораторного центра </p><p>SPIN: 4542–3588, Author ID: 760427 344037, Российская Федерация, г. Ростов-на-Дону, ул. 14-я линия, д. 63 </p></bio><bio xml:lang="en"><p>Cand. Sci. (Biol.), Researcher at the Testing Laboratory Center </p><p>SPIN: 4542–3581, Author ID: 760427</p><p>63 14 line str., Rostov-on-Don 344037, Russian Federation </p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «НМИЦ онкологии» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Centre for Oncology of the Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>02</day><month>06</month><year>2020</year></pub-date><volume>1</volume><issue>2</issue><fpage>28</fpage><lpage>35</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Жукова Г.В., Шихлярова А.И., Сагакянц А.Б., Протасова Т.П., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Жукова Г.В., Шихлярова А.И., Сагакянц А.Б., Протасова Т.П.</copyright-holder><copyright-holder xml:lang="en">Zhukova G.V., Shikhliarova A.I., Sagakyants A.B., Protasova T.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.cancersp.com/jour/article/view/55">https://www.cancersp.com/jour/article/view/55</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>ксенографты злокачественных опухолей человека</kwd><kwd>мыши BALB/c nude</kwd><kwd>методы гуманизации</kwd><kwd>мезенхимальные стволовые клетки</kwd><kwd>иммунокомпетентные животные</kwd><kwd>сибсы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>xenografts of human malignant tumors</kwd><kwd>BALB/c nude mice</kwd><kwd>humanization methods</kwd><kwd>mesenchymal stem cells</kwd><kwd>immunocompetent animals</kwd><kwd>sibs</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">работа проведена при поддержке ФГБУ «НМИЦ онкологии» Минздрава России</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Williams JA. 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