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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cancersp</journal-id><journal-title-group><journal-title xml:lang="ru">Южно-Российский онкологический журнал/ South Russian Journal of Cancer</journal-title><trans-title-group xml:lang="en"><trans-title>South Russian Journal of Cancer</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2686-9039</issn><publisher><publisher-name>АНО "Перспективы онкологии"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.37748/2687-0533-2020-1-3-6</article-id><article-id custom-type="elpub" pub-id-type="custom">cancersp-74</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Клинические наблюдения</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASE REPORTS</subject></subj-group></article-categories><title-group><article-title>Резорбция костного лоскута после костнопластической краниотомии в плановой нейрохирургии (случай из практики)</article-title><trans-title-group xml:lang="en"><trans-title>Bone flap resorption after complications of in elective neurosurgery (case study)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2937-0470</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Росторгуев</surname><given-names>Э. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Rostorguev</surname><given-names>E. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Росторгуев Эдуард Евгеньевич – к.м.н., заведующий отделением нейроонкологии. SPIN: 8487-9157, AuthorID: 794808, Scopus Author ID: 57196005138</p><p>344037, г. Ростов-на-Дону, ул. 14-я линия, д. 63</p></bio><bio xml:lang="en"><p>Eduard E. Rostorguev – Cand.Med.Sc., Head of Neurooncological Department. AuthorID: 794808, Scopus Author ID: 57196005138</p><p>63 14 line str., Rostov-on-Don 344037</p></bio><email xlink:type="simple">ed.rost@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2337-326X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузнецова</surname><given-names>Н. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuznetsova</surname><given-names>N. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кузнецова Наталья Сергеевна – врач-онколог, сотрудник отделения нейроонкологии. SPIN: 8553-3081, AuthorID: 920734</p><p>344037, г. Ростов-на-Дону, ул. 14-я линия, д. 63</p></bio><bio xml:lang="en"><p>Natalia S. Kuznetsova – oncologist, Neurooncological Department. SPIN: 8553-3081, AuthorID: 920734</p><p>63 14 line str., Rostov-on-Don 344037</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ядрышникова</surname><given-names>Г. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Yadryshnikova</surname><given-names>G. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ядрышникова Галина Николаевна – врач анестезиолог-реаниматолог, сотрудник отделения анестезиологии и реанимации. SPIN: 5963-0447, AuthorID: 961525</p><p>344037, г. Ростов-на-Дону, ул. 14-я линия, д. 63</p></bio><bio xml:lang="en"><p>Galina N. Yadryshnikova – anesthesiologist and reanimatologist. SPIN: 5963-0447, AuthorID: 961525</p><p>63 14 line str., Rostov-on-Don 344037</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «НМИЦ онкологии» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Centre for Oncology of the Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>27</day><month>08</month><year>2020</year></pub-date><volume>1</volume><issue>3</issue><fpage>60</fpage><lpage>66</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Росторгуев Э.Е., Кузнецова Н.С., Ядрышникова Г.Н., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Росторгуев Э.Е., Кузнецова Н.С., Ядрышникова Г.Н.</copyright-holder><copyright-holder xml:lang="en">Rostorguev E.E., Kuznetsova N.S., Yadryshnikova G.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.cancersp.com/jour/article/view/74">https://www.cancersp.com/jour/article/view/74</self-uri><abstract><p>Костно-пластическая краниотомия, предполагающая выпиливание свободного костного лоскута для осуществления доступа к патологическому интракраниальному очагу с его реимплантацией в конце оперативного вмешательства, является неотъемлемой частью плановых операций в современной нейрохирургической практике.</p><p>Завершение плановой нейрохирургической операции установкой костного лоскута в трепанационное окно с использованием различных методик фиксации в условиях отсутствия выраженного отека головного мозга или опухолевой деструкции кости является стандартной процедурой и обеспечивает восстановление формы черепа, ликвородинамики и перфузии головного мозга.</p><p>По данным литературы, частота развития асептического воспаления с последующей резорбцией костного лоскута после выполнения костно-пластической краниотомии в плановой нейрохирургии четко не определена. Проведенный анализ базы медицинских публикаций PUBMED указывает на единичные сообщения о резорбции костного лоскута после выполнения плановой костно-пластической краниотомии. При анализе в отечественной базе E-Library сообщений о резорбции костного лоскута после плановых костно-пластических краниотомий не обнаружено.</p><p>Вследствие ограниченного числа сообщений о резорбции костного лоскута после выполнения костнопластической краниотомии в плановой нейрохирургии на данный момент остается неясной патофизиология данного процесса.</p><p>Тем не менее, представленное осложнение костно-пластической краниотомии может привести к дислокации костного лоскута, развитию локального болевого синдрома, косметическому дефекту, нарушению ликвородинамики.</p><p>В статье описывается пример частичной резорбции костного лоскута после костно-пластической краниотомии, по поводу удаления менингиомы верхнего сагиттального синуса в средней трети, что в последующем в свою очередь потребовало проведения ряда повторных нейрохирургических вмешательств. Лечение завершилось удалением частично резорбированного костного лоскута с последующей имплантацией индивидуально изготовленного сетчатого титанового имплантата.</p></abstract><trans-abstract xml:lang="en"><p>Сraniotomy is an integral part of modern elective neurosurgery which involves cutting a free bone flap to provide access to pathological intracranial structures with its reimplantation at the end of surgery.</p><p>Bone flap grafting in the trepanation window with various fixation methods in the end of elective neurosurgery in the absence of severe cerebral edema or cancer-induced bone destruction is a standard procedure that restores the skull shape, cerebrospinal fluid dynamics and cerebral perfusion.</p><p>According to the literature, the incidence of aseptic inflammation with subsequent resorption of the bone flap after craniotomy in elective neurosurgery is not clearly defined.</p><p>An analysis of medical publications in the PUBMED database showed few reports of bone flap resorption after elective craniotomy, and no reports were found after the search in the eLibrary database.</p><p>Thus, the number of reports on the bone flap resorption after craniotomy in elective neurosurgery is limited, and the pathophysiology of this process remains unclear.</p><p>However, the described complication of craniotomy can lead to the dislocation of a bone flap, the development of a local pain syndrome, a cosmetic defect, and disturbances in cerebrospinal fluid dynamics.</p><p>The article describes an example of partial resorption of a bone flap after craniotomy for the removal of meningioma in the middle third of the superior sagittal sinus, which required a number of repeated neurosurgical interventions. The treatment was finished with the removal of a partially resorbed bone flap and implantation of an individual titanium mesh implant.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>осложнения костнопластической трепанациии</kwd><kwd>осложнения костно-пластической краниотомии</kwd><kwd>резорбция краниального костного лоскута</kwd><kwd>краниопластика</kwd><kwd>пострезекционный дефект</kwd><kwd>доступы в нейрохирургии</kwd><kwd>осложнения в нейрохирургии</kwd></kwd-group><kwd-group xml:lang="en"><kwd>complications of osteoplastic trepanation</kwd><kwd>complications of craniotomy</kwd><kwd>resorption of a cranial bone flap</kwd><kwd>cranioplasty</kwd><kwd>postresection defect</kwd><kwd>accesses in neurosurgery</kwd><kwd>complications in neurosurgery</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Daou B, Zanaty M, Chalouhi N, Dalyai R, Jabbour P, Yang S, et al. 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